Healthy Directions

WholeBiotic (30 capsules, 1-month supply) | Probiotics for Digestive Health

Naturopath’s probiotic delivers probiotics, prebiotics, and postbiotics in 1 clinically studied “super strain” that's good for the whole family
Save 20% More What is AutoDelivery?
1 Box
Save $6.00
Total: $23.99
Buy 3, Get 1 FREE
Save $47.98
Total: $71.98
Best Value
Buy 5, Get 2 FREE
Save $89.97
Total: $119.96
1 Box
Total: $29.99
Buy 3, Get 1 FREE
Save $29.99
Total: $89.97
Buy 5, Get 2 FREE
Save $59.97
Total: $149.95

WholeBiotic’s unique probiotic technology supports your personal gut flora with 3 critical levels of support

  • One “super strain” probiotic supports your body’s own unique mix of beneficial flora
  • Features the #1 probiotic strain recommended by European gastrointestinal specialists in 17 countries!
  • Delivers prebiotics, probiotics, and postbiotics in just one capsule!
  • Backed by more than 22 preclinical and clinical studies
  • Helps reduce gas, bloating, and digestive discomfort and relieves occasional diarrhea
  • Great for the whole family, from children age 4+ to adults
  • Recommended by naturopathic doctor, Dr. Drew Sinatra

As a naturopathic doctor, one of the first things I ask my patients when I sit down with them is, “How’s your digestion?” The reason—your gut is the cornerstone of your health. In fact, this is the basis on which naturopathic medicine is built. And if you’re suffering from occasional bloating, gas, and just overall digestive discomfort, it could be time for a gut tune up. Because when your gut’s in tip-top shape, you feel healthy, energized, and full of life!

That’s why it was so critical for me to recommend WholeBiotic®—a nature-based probiotic for digestive health that delivers one remarkable probiotic strain with three powerful levels of digestive support—prebiotics, probiotics, and postbiotics—while also supporting your immune health. In fact, the specific “super strain” in WholeBiotic has been around for decades in Europe and is so powerful that it’s the #1 probiotic recommended by European gastrointestinal specialists in 17 countries. And now, it’s available in the US, in every dose of WholeBiotic!

Nature’s solution for digestive relief and feeling great!

As I began researching specific strains to include in digestive probiotic WholeBiotic, I knew I wanted one that was true to its natural state, with no chemicals added. As well as one that uniquely delivers the right levels of support. That’s why I decided on the highly specialized Lactobacillus rhamnosus, Lcr35. This specific Lactobacillus probiotic strain is free of additives and unhealthy filters. And, it contains beneficial prebiotics and natural postbiotics in a synergistic compound for overall digestive and immune health.

Prebiotics are important because they feed your healthy bacteria. And postbiotics are beneficial nutrients left behind in your colon when the bacteria have multiplied. These natural byproducts nourish and soothe the cells in your digestive tract—but they are stripped out of ordinary probiotic supplements! This unique, clinically studied probiotic formula helps relieve occasional gas, bloating, diarrhea, and constipation, and supports your immune system.


Your gut’s “fingerprint” determines your digestive health

Science shows that the healthiest and most beneficial probiotics for you are the ones that are already in your colon. According to the Human Microbiome Project, everyone has their own personal mix of strains—similar to a fingerprint.  That’s why taking an ordinary probiotic with a specific mix of strains may not give you the results you’re looking for—if the strains don’t match up with what your gut needs, you’re out of luck.

Backed by more than 22 preclinical and clinical studies, digestive probiotic WholeBiotic helps to feed and nourish your individual strains of probiotics so they multiply for healthier digestion and overall health and vitality. In fact, one of the reasons I chose Lcr35 was because of its unique ability to adapt to your individual gut’s “fingerprint.” As a naturopath focused on customizing guidance to each patient’s lifestyle and health care needs, you can see why I just had to get my hands on this remarkable strain!

Why WholeBiotic works so well

As a naturopath, I always tell my patients to stick to a healthy diet of whole foods—foods that are in their most natural form—not processed or refined—with no additives or preservatives. WholeBiotic is similar to this in that it is free of chemicals, additives, and fillers, making it as close to what nature intended as possible.

And, the technology behind this digestive probiotic is unique in that its exclusive manufacturing and “training” process helps Lcr35 target your personal gut flora. No other probiotic uses this proprietary process…

STEP 1. Natural fermentation. Lcr35 are cultured in a nature-inspired, pharmaceutical-grade medium with no chemicals added. This lets the healthy bacteria grow stronger and multiply, so they can adapt and thrive—naturally—once they reach your colon. And it allows prebiotics and postbiotics to remain in the final product.

STEP 2. Special “training.” The medium is kept intact so all the digestive benefits are preserved. And Lcr35 is subjected to an exclusive combination of “stimuli” designed to help:

  • Enhance its ability to survive the acid barrier in your stomach, delivering the healthy bacteria to your colon.
  • Make it sticky so it adheres to your colon wall and helps crowd out the nonbeneficial bacteria.
  • Relieve occasional diarrhea, excess bloating, and periodic constipation.
  • Stimulate the growth of your own personal healthy bacteria.

STEP 3. Freeze-dry. Lcr35 and the prebiotics and postbiotics are freeze-dried in their complete natural state. Some probiotics on the market contain extra ingredients that dilute the probiotic powder and make it less effective. Lcr35 is left untouched, making it more powerful, and the live bacteria are preserved naturally, with no refrigeration required.

Plus, Lcr35 comes from a single manufacturer in France where every batch is DNA tested for purity and consistency. You’ll always know you’re getting an effective product you can trust.

Safe, effective, and gentle, just as nature intended!

Whether you have problems with gas, bloating, periodic constipation and hard stools, occasional diarrhea, or discomfort, this remarkable digestive probiotic helps your own indigenous, unique combination of friendly, beneficial bacteria prosper and multiply for healthy digestion. In fact, WholeBiotic is so effective the benefits can last for days after you stop taking it. So you’re always covered if you forget your daily dose!

Plus, with an effective low dose, WholeBiotic can be used by the whole family. It has been used worldwide for 60 years in more than 17 countries. And it's given to children in developing countries who greatly benefit from it's powerful digestion and immune support. No adverse events have ever been documented.

Dr. Drew Sinatra Says:


"When you feel gassy and bloated, or are struggling with occasional irregularity, it’s not just uncomfortable; it could be a sign your digestive system needs a tune-up. That’s when WholeBiotic comes to the rescue!"

—Dr. Drew Sinatra


WholeBiotic has been studied to promote healthy, comfortable digestion and give you peace of mind knowing your immune system is getting the support it needs.

WholeBiotic WholeBiotic

Dr. Drew Sinatra Says:


"When you feel gassy and bloated, or are struggling with occasional irregularity, it’s not just uncomfortable; it could be a sign your digestive system needs a tune-up. That’s when WholeBiotic comes to the rescue!"

—Dr. Drew Sinatra


Ingredients and Dosage

Doctor's Suggested Use: Adults and children 4 and older: Take 1 capsule daily prior to breakfast or lunch. For extra support, take 2 capsules daily.

Serving Size: 1 Capsule
Servings Per Container: 30

Ingredient Amount Per Serving % DV
Lcr35®‡ WholeBiotic Culture Matrix
(Lactobacillus rhamnosus)
375 mg *
* Daily Value (DV) not established

Other ingredients: Fructooligosaccharides, potato starch, hydroxypropyl methylcellulose, ascorbic acid, lactose, maltodextrin, magnesium stearate, caramel (color).

NOTE: If you are pregnant or lactating, consult a health care professional before taking this product.

Keep out of reach of children.

Lcr35® is a registered trademark of Probionov LLC.

Product of France

Science and Quality

In a prospective, randomized, double-blind, placebo-controlled pilot study, 205 subjects consumed 2 billion CFU/day (1 billion CFU twice daily) of WholeBiotic or placebo from the third day after admission to discharge from the hospital. WholeBiotic was effective in promoting the colonization of good bacteria in the respiratory tract, supporting immune health and respiratory function.1

In a double-blind, randomized, controlled study, 986 children (preschoolers) were randomized in 4 groups. 193 served as the control group, 285 consumed 200 million CFU/day of WholeBiotic, 222 received 30 billion of L. rhamnosus, and 286 received 100 billion CFU/day of multiple probiotics consisting of 12 strains, 7 being Lactobacillus. All groups consumed their respective probiotic supplement 5 days a week for a 3-month period and a 7-month period. Each group served in 2 baseline periods before the start of the 3- and 7-month interventions.  Results showed WholeBiotic can promote a normal/healthy immune response as well as a healthy GI tract.2

In a randomized, controlled, parallel-arm, dose-response trial, 12 healthy adult subjects received either 100 million, 10 billion, or 1 trillion CFU/day of WholeBiotic for two, 7-day periods separated by a 3-week washout. It was concluded that WholeBiotic can survive in the gastrointestinal tract and even help proliferate indigenous Lactobacillus populations. This suggests that WholeBiotic has a prolonged effect on the level of bacteria within the GI tract. 3

In a randomized, double-blind pilot study, 50 subjects received Lcr35 at 600 million CFU/daily or placebo for 4 weeks. Diarrhea and abdominal discomfort was reduced in the subjects taking Lcr35, while there was no change in the placebo group. 4

1 Forestier C, et al. Crit Care. 2008;12(3):R69.
2 Lin JS, et al. Vaccine. 2009;27(7):1073 –79.
3 De Champs C, et al. J Clin Microbiol. 2003;41(3):1270 –73.
4 Dapoigny M, et al. World J Gastroenterol. 2012;18(17):2067–75.

Product Quality

  • Manufactured to exacting standards using highest quality raw materials
  • Produced in accordance with our strict Standard Operating Procedures (SOPs) that meet or exceed those set by the FDA’s Good Manufacturing Practices
  • Every batch tested to verify purity and potency specifications are met
  • Quality assured with our Triple-Testing Philosophy™
  • Backed by our 100% satisfaction guarantee

Customer Reviews