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Dr. Stephen Sinatra

Advanced Lung & Bronchial Support

Clinically validated key ingredients combined with traditional herbal extracts to support easy, clear breathing and optimal lung health

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Additional Product Details

Year-round support for clear breathing and healthy lungs

Cardiologist formulated

Respiratory Health

Lung function

Advanced heart health

Advanced Lung & Bronchial Support

Clear breathing for a more active you!

In a randomized, double-blind, placebo-controlled clinical study, 29 subjects with respiratory concerns took AlvioLife—the key ingredient in Advanced Lung & Bronchial Support—daily for 8 weeks. The results: Their Activity Limitation Score (ALS) improved significantly, meaning they were able to be much more active after using AlvioLife! Plus, their emotional well-being, clear breathing and overall lung health improved!

Bar diagrammatic representation of the mean change in Activity Limitation Score after supplementation with placebo or AlvioLife. Each bar represents mean = SD.
*p<0.05; ** <0.005;n=13

Healthier lungs & a healthier heart

Your lungs are important for so much more than just breathing. They are also directly connected to your heart. Supplementing with the right ingredients such as boswellia, quercetin, and N-Acetyl L-Cysteine, helps support your lungs, and ultimately your entire cardiovascular system.

Everyday support…even during seasonally challenging times

If you find yourself struggling on seasonally challenging days or when exposed to certain environmental factors, you can count on Advanced Lung & Bronchial Support to give you the support you need, every day.

AlvioLife for optimal respiratory health all year long.

AlvioLife for optimal respiratory health all year long.

A patent-pending blend of Boswellia and quince fruit extract, AlvioLife has been shown in a clinical study to be effective in helping to maintain clear and open airways, normal lung function, a healthy respiratory system, and a healthy inflammatory response, in just 8 weeks! Plus, helps cope with the respiratory effects of everyday environmental challenges.

Potent amino acids for healthy mucus levels

Potent amino acids for healthy mucus levels

N-Acetyl L-Cysteine (NAC) has been shown to help balance healthy mucus and sputum levels in the respiratory tract. NAC is also a potent antioxidant that supports overall lung health.

Quercetin for a healthier cardiovascular system

Quercetin for a healthier cardiovascular system

Quercetin, a potent antioxidant found in onions, apples, berries, and teas and red wine, supports cardiovascular health by supporting endothelial function—which has an impact on your blood vessels and blood flow.

2 powerful nutrients

Traditionally used herbs for lung health

A blend of tried-and-true herbs—Astragulus, Marshmallow, and Yerba Santa have been traditionally used to help support lung health.

Formulated by Integrative Cardiologist Stephen Sinatra, M.D.

A true pioneer, Dr. Sinatra spent more than 40 years in clinical practice, including serving as an attending physician and chief of cardiology at Manchester Memorial Hospital, then going on to formulate his advanced line of heart health supplements. His integrative approach to heart health has changed the lives of hundreds of thousands.

Dr. Sinatra

Ingredients and Dosage

Doctor's Suggested Use: Take 2 capsules once daily with a meal.

Serving Size: 2 Capsules
Servings Per Container: 30

IngredientAmount Per Serving% DV
N-Acetyl L-Cysteine600 mg*
Quercetin250 mg*
Bromelain (from pineapple stem)200 mg*
AlvioLife® Herbal Blend
Boswellia Extract (oleo-gum resin), Quince Extract (fruit)
200 mg*
Traditional Herbal Blend
Marshmallow Extract (root), Yerba Santa Extract (leaf), Astragalus Extract (root)
200 mg*
* Daily Value (DV) not established

Other ingredients: Gelatin, magnesium stearate, silica

Precautions: Consult a health care practitioner before use if you are pregnant or nursing, have a serious medical condition, or use any medications.


  • Gluten Free

AlvioLife® is a registered trademark of PLT Health Solutions-Laila Nutra, LLC and is used under license. International patents pending.
Due to the nature of these ingredients, color variation may occur.

Science and Quality

Advanced Lung & Bronchial Support combines clinically validated ingredients with tried-and-true traditional herbs for optimal lung function, clear breathing, and more!

AlvioLife® (200 mg)

AlvioLife is a clinically validated herbal blend of Boswellia and Quince fruit extracts combined to promote optimal lung and respiratory health. In a randomized, double-blind, placebo-controlled clinical study, 36 subjects were given 200 mg of AlvioLife®—the same amount you get in one daily dose of Advanced Lung & Bronchial Support—daily for 8 weeks. The results? Their Activity Limitation Score (ALS) improved significantly, meaning trial participants were able to be much more active after using AlvioLife! These results are also why I feel this ingredient is ideal for including in a lung health support formula.1

  • Boswellia serrata—is a deciduous tree that grows naturally in dry mountainous regions of India, Northern Africa, and the Middle East. The traditional use of Boswellia dates to the ancient Ayurvedic medicinal texts written 3,000 years ago. For centuries, farmers have tapped into the Boswellia tree to collect its gum resin. Boswellia is known for its incense properties and for traditionally supporting the health of various systems and organs, notably promoting a healthy inflammatory response.
  • Quince Fruit—a member of the citrus family, this fruit comes from a tree endemic to India with tremendous therapeutic potential in Ayurvedic traditions. With great mythological significance for Hindus, all parts of the plant, such as fruit, seed, bark, leaf, and root, are important ingredients in several traditional formulations in India. Traditionally, Ayurvedic practitioners have used Quince to balance and promote a healthy inflammatory response.

N-Acetyl L-Cysteine (600 mg)

N-Acetyl L-Cysteine (NAC) is a derivative of the amino acid “cysteine” that is an intermediate in synthesizing glutathione, an endogenous antioxidant. NAC has been shown to support lung health by balancing healthy mucus and sputum levels in the respiratory tract.

  • A potent antioxidant
  • Balances healthy mucus levels in the respiratory tract
  • Supports lung health

Bromelain (200 mg)

A collection of protein-digesting enzymes found in the stems of pineapple plants.

Quercetin (250 mg)

A bioflavonoid and plant compound commonly found in onions, apples, berries, nuts/seeds, tea, and red wine with potent antioxidant properties.

  • A potent antioxidant
  • Improves endothelial function
  • Supports cardiovascular health

Traditional Herbal Blend (200 mg)

This tried-and-true blend of herbs—Astragalus, Marshmallow, and Yerba Santa—has been used traditionally for years to support lung health.

  • Astragalus—A foundational herb in Chinese tradition for hundreds of years. Among its primary uses in Chinese herbal tradition was as an adaptogen and tonifying herb for the lungs.
  • Marshmallow—a perennial herb native to Europe, Western Asia, and Northern Africa. Historically, it was named by the Greeks as Althaea officinalis or “official healer.” Recent in vitro studies support its strong antioxidant properties.
  • Yerba Santa—A shrub commonly grown in California’s woodlands. This herb has been used as a beverage since the time of the ancient Indians of Brazil and Paraguay. In vitro studies show support for balancing a healthy inflammatory response.

1 Volkl KP and Schneider B. Fortschr Med 1992 Jun 30; 110(18):346–50.
2 Yugandhar, P et al Phytother Res. 2018 Jan;32(1):140-150. doi: 10.1002/ptr.5963

 

Product Quality

  • Each ingredient's potency is verified. View the Certificate of Analysis.
  • Manufactured to exacting standards using highest quality raw materials
  • Produced in accordance with our strict Standard Operating Procedures (SOPs) that meet those set by the FDA’s Good Manufacturing Practices
  • Every batch tested to verify purity and potency specifications are met
  • Quality assured with our Triple-Testing Philosophy™
  • Backed by our 100% satisfaction guarantee

What are the benefits of Dr. Sinatra Advanced Lung & Bronchial Support?

Dr. Sinatra Advanced Lung & Bronchial Support is designed to promote healthy lung function, support normal breathing, and help maintain a healthy respiratory system. Its formula combines NAC, quercetin, bromelain, clinically validated AlvioLife®, and traditional botanicals that work together to support healthy airways and the body's normal inflammatory response.
Read More
Dr. Sinatra Advanced Lung & Bronchial Support provides comprehensive nutritional support for healthy lungs and normal respiratory function. Rather than relying on a single ingredient, it combines several evidence-backed nutrients that support different aspects of respiratory wellness.

N-Acetyl L-Cysteine (NAC) supports the body's production of glutathione, one of the body's primary antioxidants. The formula also features clinically validated AlvioLife®, a proprietary blend of Boswellia serrata and Bael fruit extracts shown in clinical research to support measures of respiratory health and quality of life when used at the same daily dose included in this product. Traditional herbs including marshmallow root, yerba santa, and astragalus provide additional botanical support for a comprehensive formula that supports healthy respiratory tissues.

How does Advanced Lung & Bronchial Support help support healthy breathing?

The formula supports healthy breathing by helping maintain healthy airways, supporting antioxidant defenses, promoting a healthy inflammatory response, and supporting normal respiratory function. Key ingredients work together to support respiratory wellness instead of focusing on only one pathway.
Read More
Healthy breathing depends on many factors, including healthy airway tissues, balanced inflammatory responses, antioxidant protection, and normal lung function. This formula addresses each of these areas through a combination of complementary ingredients.

Alongside NAC, quercetin, and bromelain, AlvioLife® is included in this formula at the clinical dose and has been researched for its ability to support respiratory comfort and quality-of-life measures related to bronchial health. Traditional herbs such as marshmallow root and yerba santa have long histories of use for supporting respiratory wellness and soothing healthy airway tissues. Together, these ingredients provide broad nutritional support for everyday respiratory health.

What makes this lung support formula different from other respiratory supplements?

Unlike many respiratory supplements that rely on one or two ingredients, this formula combines clinically validated AlvioLife®, plus NAC, quercetin, bromelain, and traditional botanicals to provide comprehensive nutritional support for healthy lung function and normal breathing.
Read More
Many lung health supplements focus primarily on a single antioxidant or herbal extract. Dr. Sinatra Advanced Lung & Bronchial Support takes a broader approach by combining multiple ingredients in one formula that supports respiratory health.

The formula includes 600 mg of NAC, a well-known precursor to glutathione; quercetin and bromelain for antioxidant support; and clinically researched AlvioLife®, a proprietary botanical blend evaluated at the same daily dose used in this formula. The addition of marshmallow root, yerba santa, and astragalus creates an even more comprehensive respiratory support formula that combines modern nutritional science with traditional botanical ingredients. This multi-ingredient strategy is designed to support overall lung and bronchial wellness rather than targeting only one aspect of respiratory health.

What is NAC, and why is it included in this formula?

N-Acetyl L-Cysteine (NAC) is an amino acid derivative that helps the body produce glutathione, one of its most important antioxidants.
Read More
NAC (N-Acetyl L-Cysteine) is one of the most researched nutrients for antioxidant and overall wellness. It serves as a precursor to glutathione, the body's master antioxidant, which helps protect cells from oxidative stress caused by everyday environmental exposures.

Dr. Sinatra Advanced Lung & Bronchial Support provides 600 mg of NAC per serving, paired with complementary antioxidants and botanical ingredients to create a formula that supports healthy breathing from multiple angles.

What is AlvioLife®, and what makes it unique?

AlvioLife® is a proprietary blend of Boswellia serrata and Bael fruit extracts. It has been clinically validated for supporting bronchial health and respiratory quality of life and is included in this formula at the same daily dose used in published clinical research.
Read More
AlvioLife® is a patented botanical ingredient combining Boswellia serrata gum resin extract with Bael tree fruit extract. Unlike many proprietary blends, AlvioLife® has been evaluated in a placebo-controlled clinical study at the same 200 mg daily dose provided in Dr. Sinatra Advanced Lung & Bronchial Support.

In that study, participants experienced significant improvements in several respiratory quality-of-life measures, including asthma symptom scores, emotional function, activity limitation, environmental stimuli scores, and peak expiratory flow rate over the course of the study. The researchers did not observe a significant change in forced expiratory volume, providing an important context for the ingredient's demonstrated benefits. Including AlvioLife® at its clinical dose helps distinguish this formula from many general respiratory supplements.

Can Advanced Lung & Bronchial Support help during seasonal respiratory challenges?

Advanced Lung & Bronchial Support provides nutritional support for healthy respiratory function throughout the year, including during seasonal environmental changes. Its blend of antioxidants, botanicals, and respiratory-support nutrients helps maintain healthy airways and supports the body's normal respiratory system and breathing.
Read More
Seasonal changes can increase exposure to pollen, dust, and other environmental irritants that place additional demands on the respiratory system. While Advanced Lung & Bronchial Support is not intended to treat seasonal allergies, it provides nutritional support that helps maintain healthy respiratory tissues throughout the year.

AlvioLife® provides clinically validated botanical support for bronchial wellness. This comprehensive formula helps maintain healthy breathing during everyday environmental challenges.

Can I take Advanced Lung & Bronchial Support every day?

Yes. Advanced Lung & Bronchial Support is designed for daily use. The recommended serving is two capsules once daily with food, making it easy to incorporate into a wellness routine that supports healthy lungs and normal respiratory function.
Read More
Consistent daily use is often the best approach when taking nutritional supplements designed to support lasting health. Dr. Sinatra Advanced Lung & Bronchial Support is formulated for everyday use, with a recommended serving of two capsules once daily with food.

Daily supplementation provides ongoing nutritional support for antioxidant defenses, healthy inflammatory response, normal respiratory system, and healthy lung function. As with any dietary supplement, individuals who are pregnant, nursing, taking medications, or under medical supervision should consult their healthcare provider before beginning a new supplement routine.

Who should consider taking Advanced Lung & Bronchial Support?

This formula is designed for adults who want to proactively support healthy lung function, maintain normal breathing, and promote respiratory wellness. It may be especially appealing to those seeking antioxidant support or nutritional support for healthy airways as part of an active lifestyle.
Read More
Healthy lungs become increasingly important as we age and as we're exposed to everyday environmental factors such as pollution, dust, and seasonal irritants. Advanced Lung & Bronchial Support is formulated for adults who want comprehensive nutritional support for respiratory wellness before problems develop.

Its combination of NAC, quercetin, bromelain, clinically validated AlvioLife®, and traditional respiratory botanicals supports healthy airways, antioxidant defenses, and normal respiratory function. The formula may be appropriate for individuals looking to maintain healthy breathing, support lung health all throughout the year, or complement a broader healthy lifestyle that includes exercise, good nutrition, and avoiding smoking or other respiratory irritants.

How long does it take to notice benefits from Advanced Lung & Bronchial Support?

Results vary from person to person. Because this supplement supports lasting respiratory wellness rather than providing immediate relief, consistent daily use is recommended. Individual factors such as age, lifestyle, overall health, and environmental exposures can all influence when benefits are noticed.
Read More
Dietary supplements work by supporting the body's normal physiological processes, and the timeline for experiencing benefits can differ among individuals. Factors such as nutritional status, age, activity level, environmental exposures, and overall respiratory health all play a role.

The clinical research on AlvioLife® reported improvements in several respiratory quality-of-life measures beginning after approximately two to four weeks, with additional improvements observed through eight weeks of supplementation at the same daily dose included in this product. While individual experiences will vary, taking Advanced Lung & Bronchial Support consistently as directed and incorporating other healthy habits can help maximize its lasting respiratory support benefits.

What traditional herbs are included in Advanced Lung & Bronchial Support?

The formula includes marshmallow root, yerba santa, and astragalus—three botanicals that have long histories of traditional use. These herbs complement the formula's clinically validated key ingredient to create a formula that helps support healthy airway function and overall respiratory health.

Is Advanced Lung & Bronchial Support only for older adults?

No. While lung health naturally becomes more important with age, adults of many ages can benefit from supporting healthy respiratory function. The formula is designed for any adult looking to maintain healthy lungs and support normal breathing as part of a healthy lifestyle.
Read More
Respiratory wellness is important throughout adulthood, not just later in life. Everyday exposure to environmental factors can place ongoing demands on the lungs regardless of age.

Advanced Lung & Bronchial Support is formulated for adults who want proactive nutritional support for healthy lung function and normal breathing. Whether you enjoy outdoor activities, live in an urban environment, travel frequently, or simply want to support healthy aging, the combination of antioxidants, clinically backed key botanicals, and traditional herbs provides comprehensive support for respiratory wellness. Maintaining healthy lungs today can help support lasting respiratory health for years to come.

Can Advanced Lung & Bronchial Support be taken with other Healthy Directions supplements?

In many cases, yes. Advanced Lung & Bronchial Support can often be incorporated into a broader wellness routine alongside other Healthy Directions supplements. However, because everyone's health needs are different, it's always best to review your supplement regimen with your healthcare provider.
Read More
Many Healthy Directions customers use targeted supplements to support multiple aspects of their health, including cardiovascular, immune, joint, vision, and digestive wellness. Advanced Lung & Bronchial Support is designed to complement an overall healthy lifestyle and may fit well into a comprehensive wellness routine for anyone seeking lung health and respiratory system support.

If you take prescription medications or other dietary supplements containing similar ingredients, consult your healthcare provider before adding any new supplement. They can help determine whether your current regimen is appropriate for your individual needs. Following the product's recommended serving directions and sharing your supplement routine with your healthcare provider can help ensure you're making informed choices about your health.

Why is antioxidant support important for lung health?

The lungs are continuously exposed to oxygen and environmental particles, making antioxidant protection especially important. Antioxidants help protect cells from oxidative stress, supporting healthy lung cells and normal respiratory function as part of overall wellness.
Read More
Every breath exposes the lungs to oxygen as well as environmental and other airborne particles. Over time, these exposures can contribute to oxidative stress, which is why antioxidant nutrients play an important role in maintaining respiratory health.

Advanced Lung & Bronchial Support includes several antioxidant-supporting ingredients. NAC is a known precursor to glutathione, one of the body's primary antioxidants. Quercetin provides additional antioxidant protection, while the botanical ingredients in the formula contribute complementary phytonutrients that support healthy cellular function. By helping defend cells against everyday oxidative stress while also supporting healthy inflammatory response and normal respiratory function, the formula provides comprehensive nutritional support for lasting lung wellness.

Does Advanced Lung & Bronchial support healthy lung function as you age?

Yes. Healthy lung function naturally changes with age, making proactive nutritional support increasingly important. Advanced Lung & Bronchial Support provides antioxidants, clinically backed key botanicals, and targeted nutrients that help support normal breathing, healthy respiratory tissues, and overall lung wellness throughout healthy aging.
Read More
Just as heart, joint, and eye health become priorities with age, maintaining healthy lung function is an important part of healthy aging. Over time, everyday exposure to environmental irritants and oxidative stress can affect respiratory wellness.

Advanced Lung & Bronchial Support was formulated to help support healthy lungs over the long term. NAC is a known precursor to glutathione, an antioxidant that helps protect cells from oxidative stress. Quercetin and bromelain are also included, while AlvioLife® provides clinically backed botanical support for healthy bronchial function and respiratory quality-of-life measures. Traditional herbs including marshmallow root, yerba santa, and astragalus further support overall wellness. Together, these ingredients provide comprehensive nutritional support for maintaining healthy breathing as part of an active lifestyle.

Does this formula support both the lungs and bronchial airways?

Yes. The formula is designed to support the entire respiratory system, including healthy lung tissue and bronchial airways. Its combination of NAC, AlvioLife®, quercetin, bromelain, and traditional herbs provides comprehensive respiratory support rather than focusing on a single aspect of lung health.
Read More
Healthy breathing depends on more than the lungs alone. The bronchial airways play a critical role in moving air efficiently, while healthy lung tissue supports oxygen exchange. Advanced Lung & Bronchial Support was formulated to provide nutritional support for both.

AlvioLife® has been clinically backed for supporting bronchial wellness and respiratory quality-of-life measures at the same daily dose found in this product. By addressing multiple components of respiratory wellness, the formula provides broad nutritional support for comfortable, healthy breathing.

What lifestyle habits work best with Advanced Lung & Bronchial Support?

Advanced Lung & Bronchial Support works best as part of a healthy lifestyle that includes regular physical activity, a nutrient-rich diet, avoiding smoking, staying hydrated, and minimizing exposure to environmental pollutants whenever possible.
Read More
Dietary supplements are most effective when combined with healthy daily habits. Regular exercise helps support cardiovascular fitness and healthy lung capacity, while staying hydrated supports normal respiratory function. Eating a diet rich in colorful fruits and vegetables provides additional antioxidants that complement the ingredients in this formula.

Avoiding smoking and limiting exposure to secondhand smoke, excessive dust, and air pollution also help protect lung health over time. Advanced Lung & Bronchial Support provides targeted nutritional support through NAC, quercetin, bromelain, clinically backed AlvioLife®, and traditional herbs, making it an excellent complement to these healthy lifestyle practices rather than a substitute for them.

Is Advanced Lung & Bronchial Support backed by scientific research?

Yes. The formula contains several well-researched ingredients, including clinically backed AlvioLife®, which has been evaluated in human clinical research at the same daily dose included in this product.
Read More
Dr. Sinatra Advanced Lung & Bronchial Support was developed using ingredients selected for their scientific support and complementary roles in respiratory wellness.

A key differentiator is AlvioLife®, a proprietary blend of Boswellia serrata and Bael fruit extracts. In a placebo-controlled human clinical study, participants taking 200 mg daily—the same amount included in this formula—experienced significant improvements in multiple respiratory quality-of-life measures and peak expiratory flow rate over the study period, although no significant improvement was observed in forced expiratory volume. This commitment to clinically backed key ingredients helps distinguish the formula from many standard respiratory supplements.

Why choose Dr. Sinatra Advanced Lung & Bronchial Support?

Dr. Sinatra Advanced Lung & Bronchial Support offers comprehensive respiratory wellness support by combining key ingredients with trusted nutritional science. Rather than relying on a single ingredient, it delivers a multi-targeted approach to supporting healthy lungs, normal breathing, and healthy bronchial function.
Read More
Dr. Sinatra Advanced Lung & Bronchial Support stands apart because it brings together several complementary ingredients in one thoughtfully formulated supplement. It provides 600 mg of NAC, quercetin and bromelain for antioxidant support, AlvioLife® at the researched daily dose, and a traditional herbal blend featuring marshmallow root, yerba santa, and astragalus.

Instead of focusing on only one aspect of respiratory health, the formula supports healthy lung function, bronchial wellness, antioxidant defenses, and normal breathing through multiple nutritional pathways. For adults looking to proactively maintain respiratory health, it offers a comprehensive, science-informed approach consistent with Dr. Sinatra's philosophy of supporting whole-body wellness.

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