Levagen®
While Levagen+ does act on the same endocannabinoid pathways that CBD does, these instead involve the pathways in which your body feels discomfort.
Levagen+ contains palmitoylethanolamide (PEA), which is normally produced by the body and is also a common component of food. PEA is safe, legal and has been determined to be GRAS (Generally Recognized as Safe). Additionally, PEA is a well-researched compound, with a clinical study showing its effectiveness as a safe nutrient for easing discomfort.
NEM® natural eggshell membrane
Studies show 500 mg daily helps relieve everyday joint aches and discomfort, including a study in post-menopausal women that shows 500 mg daily of NEM helps decrease post-exercise induced joint discomfort.1,2
It’s also been found in clinical studies in healthy individuals as well as in those with specific joint health concerns that NEM eggshell membrane supports joint health by reducing discomfort and stiffness.3,4
FruiteX-B® calcium fructoborate complex
Studies show that calcium fructoborate complex modulates key markers associated with inflammatory health and is a fast-acting, lasting nutritional compound beneficially impacting joint health.
FruiteX-B has also been shown to support a healthy inflammatory response by maintaining healthy levels of inflammatory markers such as CRP, IL-6, and IL-β1. In a study, support for joint health, function, and mobility was observed after only one week of supplementation in healthy subjects with joint discomfort.5,6,7
Furthermore, a study showed that FruiteX-B helps to increase the absorption of vitamin D.8
Sensoril® Ashwagandha
Sensoril Ashwagandha is an industry-leading, branded ingredient that is clinically validated to help relieve the negative effects of stress, as well as provide a variety of other benefits, including healthy joint function and mobility. Sensoril, invented by Fulbright Scholar Dr. Shibnath Ghosal, is a multi-patented, natural, standardized extract of ashwagandha (also called Indian ginseng or winter cherry).
Ashwagandha, a revered botanical with adaptogenic properties, has been one of the primary ingredients used in India’s Ayurvedic traditional system of health and healing for thousands of years. Adaptogens are a select group of botanicals that help provide resistance to stress and bring the body back into balance.
Sensoril Ashwagandha helps:
- Maintain healthy cortisol levels
- Reduce stress and occasional anxiousness
- Boost mood & mental health
- Reduce fatigue and irritability
- Improve focus and concentration
- Support healthy sleep quality
- Support joint mobility, function & comfort
It has also been found in a clinical study to support multiple cardiovascular health parameters including blood pressure, blood sugar, cholesterol, triglycerides and inflammatory marker C-reactive protein, or CRP.
9
DigeZyme® Enzyme Blend
DigeZyme® is a unique natural, vegan, non-GMO multi-enzyme complex of five digestive enzymes including alpha amylase, neutral protease, cellulase, lactase, and lipase. These enzymes help to digest foods including starches, proteins and fats for healthy, comfortable digestion. DigeZyme also supports muscle comfort and soreness after exercise.
Two randomized double-blind clinical studies have been conducted on DigeZyme. One shows beneficial effects on digestive symptoms. The other study shows benefits for parameters of muscle discomfort, soreness, and tenderness, following exercise in healthy males.10
1Ruff KJ, et al. Clin Rheumatol. 2009;28(8):907–14.
2Ruff KJ, et al. Clin Interv Aging. 2018;13:285–295.
3Ruff KJ, et al. Clin Rheumatol. 2009;28(8):907–14.
4Ruff KJ, et al. Clin Interv Aging. 2009;4:235-40.
5Rogoveanu OC, et al. Biol Trace Elem Res. 2015;163:124–131.
6Pietrzkowski, Z, et al. Clin Interv Aging. 2014;9:895-9.
7Pietrzkowski, Z, et al. J Aging Res Clin Practice. 2018;7:31–36.
8Reyez-Izquierdo T, et al. Am J. Biomed Sci. 2012;4(2):111-22.
9Auddy, B. et al. JANA. 2008;11(1):51–57.
10Majeed M, et al. Sports Nutr Ther. 2016;1(3). and Majeed M, et al. J Med Food. 2018;21(11):1120–1128.
