Item #ESJ01

Dr. David Williams

Joint Advantage Gold 5X

Tried everything? This powerful formula relieves joint discomfort starting in as little as 7 days

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Joint Advantage Gold ® 5X quickly relieves everyday joint discomfort

Joint Advantage Gold 5X gives you fast relief from joint discomfort and works to support healthy joints. It combines clinically researched AprèsFlex®, NEM® eggshell membrane, glucosamine, and a proprietary blend of herbs and enzymes to provide everyday relief.

Fast, clinically researched natural joint soother

No more waiting weeks or months for soothing relief. AprèsFlex, the superstar of Joint Advantage Gold 5X, is clinically shown to alleviate joint discomfort and stiffness—starting in as little as 7 days.

AprèsFlex is the next generation of Boswellia serrata extract. It works faster and better than anything Dr. Williams investigated. Years ago during Dr. Williams' travels to India, he learned that the gum resin from the boswellia tree has been used in Ayurvedic medicine for over 3,000 years to soothe joints.

The problem is the standard form of boswellia is poorly absorbed by your bloodstream because it contains a glycoprotein (P-gp) that acts as a barrier. But, for AprèsFlex, the extract is enriched with an additional blend of natural compounds from the boswellia tree, which inhibit the glycoprotein and significantly improve absorption.

Clinical research shows reduction in discomfort and stiffness

In a double-blind, randomized, placebo-controlled study, 59 subjects with stiff, achy joints took 100 mg of AprèsFlex or a placebo daily for 30 days. Three tests were used to measure discomfort, stiffness, and physical function—and in all 3, AprèsFlex came out on top.

  • In a measure of joint discomfort, AprèsFlex showed a 14.8% better reduction than the placebo starting in just 5 days.
  • In a measure of daily functions hindered by discomfort, AprèsFlex showed a 16.3% better reduction starting in just 5 days.
  • And after 30 days, those taking AprèsFlex reported a 40.1% improvement in joint comfort, a 41.3% improvement in stiffness, and a 38.8% improvement in functional ability.
You get the full 100 mg research dose of AprèsFlex in Joint Advantage Gold 5X.

Plus, Joint Advantage Gold 5X delivers even MORE powerful ingredients

  • Glucosamine Sulfate
    Glucosamine is one of the most recognized ingredients for joint support. Dr. Williams recommends taking 1,500 mg of glucosamine sulfate daily and that’s exactly what you get in Joint Advantage Gold 5X.
  • NEM natural eggshell membrane
    One of Dr. Williams’ classic home remedies that he’s been recommending for years is to use eggshells in a broth that you can make in your own kitchen. That’s because eggshells and the delicate membranes that line them contain joint-friendly ingredients. When put to the test, 500 mg daily helps relieve everyday joint aches and stiffness, including a decrease in discomfort. That’s the exact amount you get in Joint Advantage Gold 5X.
  • Traditional Exotic Botanicals
    Dr. Williams has traveled to Australia, Europe, and many other places researching traditionally used herbs. Wild rosella, devil’s claw, white willow, yucca, feverfew, celery seed, bromelain, and papaya are ones he’s been recommending for almost 2 decades.

Joint Advantage Gold 5X combines the tried-and-true joint supporters that Dr. Williams has discovered over the years to target everyday joint concerns: inflammatory markers; stiff, achy joints; flexibility and mobility. Taking Joint Advantage Gold 5X every day will help you stay active and independent.

Doctor's Suggested Use: Take 4 tablets daily—2 with breakfast and 2 with lunch or dinner.

Serving Size: 2 Tablets
Servings Per Container: 60

IngredientAmount Per Serving% DV
Calcium (as dicalcium phosphate, from eggshell membrane)85 mg7%
Chloride83 mg4%
Potassium88 mg2%
Glucosamine Sulfate 2KCl (from chitin)750 mg*
Eggshell Membrane (NEM®)250 mg*
HerbaZyme® Soothing Blend
Hibiscus Extract (Wild rosella, flower), Devil’s Claw Extract (root) (from Harpagophytum procumbens and Harpagophytum zeyheri), White Willow Extract (bark), Yucca Extract (root), Feverfew Extract (aerial), Celery Extract (seed), Papaya Extract (fruit), Bromelain (from pineapple)
200 mg*
Boswellia serrata Extract (gum resin)(AprèsFlex®)50 mg*
Bovine Cartilage50 mg*
*Daily Value (DV) not established.

Other ingredients: Stearic acid, microcrystalline cellulose, croscarmellose sodium, magnesium stearate, white beeswax, carnauba wax, silica
CONTAINS: SHELLFISH (shrimp, crab), EGG

Precautions: Consult a health care practitioner before use if you are pregnant or nursing, have a serious medical condition, or use any medications.

Keep out of reach of children.


  • Gluten Free

NEM® is a registered trademark of ESM Technologies, LLC and is registered in the United States and other countries.
AprèsFlex® is a registered trademark of Laila Nutraceuticals exclusively licensed to PL Thomas–Laila Nutra LLC. International patents pending.
Due to the nature of these ingredients, color variation may occur.

Science and Quality

AprèsFlex®

In laboratory animal studies, AprèsFlex showed 51.78% greater absorption of AKBA, which is an active compound that inhibits the inflammatory pathways, compared to another popular boswellia product.1 In fact, AprèsFlex was 21% more effective than the leading boswellia extract at reducing the 5-LOX enzyme that contributes to the body's inflammatory response. Plus, AprèsFlex was shown to reduce the level of 5 of the body's top inflammatory markers.

In a double-blind, randomized, placebo-controlled study, 59 subjects with stiff, achy joints took 100 mg of AprèsFlex or a placebo daily for 30 days. Three tests were used to measure discomfort, stiffness, and physical function—and in all 3, AprèsFlex came out on top.2

  • In a measure of joint discomfort, AprèsFlex showed a 14.8% better reduction than the placebo starting in just 5 days.
  • In a measure of daily functions hindered by discomfort, AprèsFlex showed a 16.3% better reduction starting in just 5 days.
  • And after 30 days, those taking AprèsFlex reported a 40.1% improvement in joint comfort… a 41.3% improvement in stiffness… and a 38.8% improvement in functional ability.

NEM® natural eggshell membrane

Studies show 500 mg daily helps relieve everyday joint aches and discomfort, including a 34% decrease in post-exercise induced joint discomfort.3,4

1Sengupta K, et al. Mol Cell Biochem. 2011;354(1–2):189–97.
2Vishal A, et al. Int J Med Sci. 2011;8(7):615–22.
3Ruff KJ, et al. Clin Rheumatol. 2009;28(8):907–14.
4Ruff KJ, et al. Clin Interv Aging. 2018 Feb 19;13:285-295.


Product Quality

  • Manufactured to exacting standards using highest quality raw materials
  • Produced in accordance with our strict Standard Operating Procedures (SOPs) that meet those set by the FDA’s Good Manufacturing Practices
  • Every batch tested to verify purity and potency specifications are met
  • Quality assured with our Triple-Testing Philosophy™
  • Backed by our 100% satisfaction guarantee

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