Item #RNX01

Dr. Julian Whitaker

Restful Night Extended Release

Extended-release formula helps you fall asleep and stay asleep longer

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Enjoy Gentle, Peaceful, More Restful Sleep

Restful Night Extended Release™ is your best support for a restful night's sleep. It combines three stress-reducing and sleep-inducing ingredients in a unique dual-layer, extended-release tablet that helps keep restless, ruminating minds calm so you can fall asleep and stay asleep longer.

The good night's sleep difference

What sets Restful Night Extended Release apart from other natural sleep supplements is the dual-layer technology that strategically delivers a divided dose of 3 mg of sleep-inducing melatonin with research levels of calming PharmaGABA®and premium Alphawave® L-theanine right when you need it. Here's how it works: First, you get a quick release of 1.5 mg of melatonin and PharmaGABA to help you fall asleep; then the second layer releases L-theanine and the remaining melatonin to help you achieve a more restful night's sleep.

Enjoy that comfy, can't-wait-to-sleep feeling

Melatonin (3 mg) decreases the time it takes to fall asleep and supports a deeper, more restful sleep.

The "sleep hormone" melatonin declines in production as you age,1 and because your body is reliant on melatonin to drive REM (Rapid Eye Movement) sleep and circadian rhythms, Dr. Whitaker made sure to include 3 mg in Restful Night Extended Release to produce healthful, satisfying sleep.

The science behind sleep

In a randomized double-blind, placebo-controlled study, participants taking 3 mg of melatonin before bedtime experienced significant increases in the amount of time spent in REM sleep while maintaining a healthy circadian rhythm.2

PharmaGABA® (100 mg) promotes relaxation to help you fall asleep

Clinical studies have shown that PharmaGABA can play an important role in reducing stress and occasional anxiousness, promote feelings of relaxation, and improve concentration. This amino acid is produced naturally in the brain, where it acts as a neurotransmitter to foster communication between nerve cells. In addition, GABA is the chief inhibitory neurotransmitter in the central nervous system and autonomic nervous system, meaning it calms down nerve cell "excitability."

The science behind stress reduction

In a study using an electroencephalogram (EEG), brain waves were evaluated in participants after either intake of 100 mg PharmGABA (the dose in Restful Night Extended Release) or a placebo. The EEG found that after taking PharmaGABA, individuals showed higher alpha waves and lower beta waves than the placebo.3 These findings suggest that PharmaGABA helps reduce stress and promote mental relaxation.

AlphaWave® L-Theanine (200 mg) promotes calmness and a reduction in anxiousness

Purified, premium L-theanine is identical to the calming amino acid found in green tea, one of nature's most effective natural relaxants. L-theanine was first isolated in 1949 and studies show that many of the benefits of green tea are derived from its L-theanine content. It works by raising your body's GABA levels, thereby promoting calming alpha-wave activity in the brain. That's why it was included as the second release in Restful Night Extended Release to continue to keep your brain in a relaxed state to help you maintain that peaceful, restful night's sleep.

The science behind sleep plus stress reduction

A placebo-controlled study suggests that 200 mg of L-theanine (the dose in Restful Night Extended Release) helps improve sleep efficiency, a measure of the amount of time between going to sleep and waking. L-theanine may also promote a better mental state upon waking.4

Restful Night Extended Release includes carefully selected complementary ingredients, designed to be non-habit forming, leaving you refreshed when you wake. If sleep issues are a concern, you will find this the perfect solution.

1Grivas TB, et al. Scoliosis 2009;4(Suppl 2):O8.
2Kunz D, et al. J Clin Endocrinol Metab. 2004;89(1):128–34.
3Abdou AM, et al.  Biofactors. 2006;26(3):201–8.
4Mason R. Alternative Complement Ther.  2001;7(2):91–5

Ingredients and Dosage

Doctor's Suggested Use: Take 1 dual layer tablet 30 minutes before bed.

Serving Size: 1 Tablet
Servings Per Container: 30

IngredientAmount Per Serving% DV
Extended Release Restful Sleep Layer201.5 mg 
L-Theanine200 mg*
Melatonin1.5 mg*
Instant Release Sleep Induction Layer101.5 mg 
Gamma Amino Butyric Acid (from fermentation) (Pharma GABA®)100 mg*
Melatonin1.5 mg*
* Daily Value (DV) not established

Other ingredients: Microcrystalline cellulose, hypromellose, dicalcium phosphate, stearic acid, croscarmellose sodium,silica, magnesium stearate, vegetable juice color, glycerin

Precautions: Consult a health care practitioner beforeuse if you are pregnant or nursing, have a serious medicalcondition, or use any medications. Do not drive oroperate heavy machinery while taking this product.

Keep out of reach of children.


  • Gluten Free

PharmaGABA® is a registered trademark of Pharma Foods International Co., Ltd. (Japan)
This product contains natural ingredients; color variations may occur.

Product Quality

  • Manufactured to exacting standards using highest quality raw materials
  • Produced in accordance with our strict Standard Operating Procedures (SOPs) that meet those set by the FDA’s Good Manufacturing Practices
  • Every batch tested to verify purity and potency specifications are met
  • Quality assured with our Triple-Testing Philosophy™
  • Backed by our 100% satisfaction guarantee

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