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Item #RNX01

Dr. Julian Whitaker

Restful Night Extended Release

Doctor-formulated, extended-release sleep solution with Melotime melatonin, PharmaGABA and L-theanine

  • Fall asleep quickly, stay asleep
  • All-night, extended release melatonin
  • Works the very first night
  • Safe, non-habit forming

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Additional Product Details

Restful Night Extended Release Works
the Very First Night to:

  • Decrease the time it takes to fall asleep
  • Ease stress, tension, and occasional anxiousness
  • Promote better overall health and daytime functioning
  • Plus, increase the length of deep, continuous, quality sleep after just one week

Enjoy gentle, peaceful, more restful sleep

Restful Night Extended Release® is your best support for a restful night's sleep, with a unique extended-release delivery that helps calm restless, ruminating minds so you can fall asleep faster and stay asleep. While most sleep supplements focus exclusively on melatonin, Restful Night Extended Release takes a holistic approach by pairing clinically validated Melotime™ melatonin with two other stress reducing and sleep-inducing ingredients, including PharmaGABA and L-theanine. Numerous research studies have indicated that PharmaGABA plays a crucial role in helping the body manage stress, promoting a calm state of mind, and enhancing the overall quality of sleep. L-theanine promotes calmness and a reduction in anxiousness. This exclusive combination helps you fall asleep faster, stay asleep, and improves your quality of sleep. And when you sleep better, you wake feeling refreshed and alert, more energetic with improved attention, less stress, and stronger overall health. And who doesn’t want all of that?

Enjoy that comfy, can't-wait-to-sleep feeling

Melotime (2 mg) and Melatonin (1 mg) decrease the time it takes to fall asleep and supports, more restful sleep.

The "sleep hormone" melatonin declines in production as you age1, yet your body relies on it to regulate circadian rhythms and the sleep cycle. That’s why Dr. Whitaker made sure to include 3 mg of melatonin in Restful Night Extended Release: 1 mg is released immediately to help you drift off to sleep, then 2 mg of Melotime melatonin releases throughout the night to promote the ideal 8-hour sleep cycle.

The science behind sleep

In a study of 555 subjects with sleep issues, 2 mg melatonin showed significant improvements after 3 weeks, with further improvements over 6 months vs. placebo, in the time it takes to fall asleep and sleep quality.2

PharmaGABA® (100 mg) promotes relaxation to help you fall asleep

Clinical studies have shown that GABA can play an important role in reducing stress and occasional anxiousness, promote feelings of relaxation, and improve task orientation. In addition, one study done on an older population showed that GABA may support sleep quality of life and reduce nighttime urinary frequency3, which means fewer interruptions and better continuous sleep. This amino acid is produced naturally in the brain, where it acts as a neurotransmitter to foster communication between nerve cells. In addition, GABA is the chief inhibitory neurotransmitter in the central nervous system and autonomic nervous system, meaning it calms down nerve cell "excitability."

The science behind stress reduction

In a study using an electroencephalogram (EEG), brain waves were evaluated in participants after taking either 100 mg PharmGABA (the dose in Restful Night Extended Release) or a placebo. The EEG found that individuals who took PharmaGABA showed higher alpha waves and lower beta waves, which suggests that PharmaGABA helps reduce stress and promote mental relaxation.

L-Theanine (200 mg) promotes calmness and a reduction in anxiousness

Purified, premium L-theanine is identical to the calming amino acid found in green tea, one of nature's most effective relaxants. L-theanine was first isolated in 1949 and studies show that many of the benefits of green tea are derived from its L-theanine content. It works by raising your body's GABA levels, thereby promoting calming alpha-wave activity in the brain. That's why it was included in Restful Night Extended Release to continue to keep your brain in a relaxed state to help you maintain that peaceful, restful night's sleep.

In a placebo-controlled study, 30 healthy subjects taking 200 mg L-theanine showed a significant improvement vs placebo in sleep latency (the amount of time it takes to fall asleep once you go to bed) and sleep disturbances.4 Restful Night Extended Release includes carefully selected complementary ingredients, designed to be non-habit forming, leaving you refreshed when you wake. If sleep issues are a concern, you will find this the perfect solution.

1Grivas TB, et al. Scoliosis 2009;4(Suppl 2):O8.
2 Wade, A. G. et al. Current Medical Research and Opinion 2011;27(1):87-98.
3 Yamatsu, A., et al. (2015). J Nutr Sci Vitaminol, 61(2), 182-7.
4 Hidese, S., et al. (2019). Nutrients, 11, 2362.

Ingredients and Dosage

Doctor's Suggested Use: Take 1 dual layer tablet 30 minutes before bed.

Serving Size: 1 Tablet
Servings Per Container: 30

Ingredient Amount Per Serving % DV
Restful Sleep Blend 202 mg *
L-Theanine 200 mg *
Extended-Release Melatonin (Melotime) 2 mg *
Instant Release Sleep Induction Blend 100 mg *
Gamma-Aminobutyric Acid (from fermentation) (PharmaGABA®) 100 mg *
Immediate Release Melatonin 1 mg *
* Daily Value (DV) not established

Other ingredients: Bilberry extract (color), dicalcium phosphate, microcrystalline cellulose, vegetable magnesium stearate, hypromellose, glycerin, hydroxypropl cellulose

Precautions: For adult use only at bedtime. This product is not to be taken by pregnant or lactating women. If you are taking medication or have a medical condition, consult a physician before using this product. Do not use in conjunction with alcoholic beverages, when driving a vehicle, or while operating machinery.

Keep out of reach of children.


  • Gluten Free

Melotime is a trademark of Inventia Healthcare, Ltd.
PharmaGABA® is a registered trademark of Pharma Foods International Co., Ltd. (Japan)
Due to the nature of these ingredients, color variation may occur.

Product Quality

  • Manufactured to exacting standards using highest quality raw materials
  • Produced in accordance with our strict Standard Operating Procedures (SOPs) that meet those set by the FDA’s Good Manufacturing Practices
  • Every batch tested to verify purity and potency specifications are met
  • Quality assured with our Triple-Testing Philosophy™
  • Backed by our 100% satisfaction guarantee

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