Item #DVI01
Doctors' Preferred
Daily5
Daily5 combines 5 clinically validated ingredients you’re not getting from your diet or your multivitamin to address the 5 BIGGEST health issues we face as we age, so you can feel good and live better than ever!
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Additional Product Details
Why Daily5 is the one thing your body NEEDS EVERY DAY!
Despite advances in modern medicine, our bodies are under more stress from more sources than ever before. And it’s almost impossible to get what your body needs to constantly repair and refuel itself from ordinary foods or multivitamins. Daily5 delivers 5 clinically validated ingredients that are absolutely essential for a vibrant, active life!
Addresses the biggest issues that slow you down
Provides what your daily multivitamin does NOT give you, but you NEED every day. It covers all the vital areas for good health and independence—your heart, joints, lipids, circulation, and energy to fuel your cells. The number of benefits improve over time to give your body what it needs to thrive every day!
What you get in each dose of Daily5
CoQ10 for cellular energy, blood pressure, arterial health and metabolic function. Magnesium glycinate for endothelial function, blood pressure, normal lipid levels and more. TamaFlex (blend of turmeric and tamarind) for fast results for joint flexibility, range of motion and mobility in 5 days. Resveratrol for circulatory health and boosts blood flow in just one hour. DOUBLE chromium promotes metabolic wellness.
Is your body secretly telling you it needs Daily5?
You wake up not feeling like yourself in the morning and need extra caffeine to get going. Your joints feel stiff and achy and it’s stopping you from getting out. Your body doesn't have the energy that it used to and you just don’t feel like yourself anymore. Daily5 was created to target all of this and more!
Ingredients and Dosage
Doctor's Suggested Use: Take three (3) vegan capsules once daily with food, along with a healthy diet and daily activity.
Serving Size: 3 Vegan Capsules
Servings Per Container:
30
| Ingredient | Amount Per Serving | % DV |
| Magnesium [as Magnesium Glycinate Complex (magnesium glycinate, magnesium oxide)] | 420 mg | 100% |
| Chromium (as Chromax® chromium picolinate, Crominex® 3+ chromium stabilized with Capros® standardized Amla Extract (fruit), PrimaVie® purified and standardized Shilajit) | 400 mcg | 1143% |
| TamaFlex® [Tamarind Extract (seed) and Turmeric Extract (rhizome)] | 250 mg | * |
| Coenzyme Q10 (as ubiquinone) | 200 mg | * |
| L-Glutathione (from fermentation)(Opitacâ„¢) | 50 mg | * |
| Resveratrol (from Japanese Knotweed Root Extract) | 75 mg | * |
| *Daily Value (DV) not established | ||
Other Ingredients: Hypromellose, microcrystalline cellulose, vegetable stearic acid, and silica.
Precautions: Consult a health care practitioner before use if you are pregnant or nursing, have a serious medical condition, or use any medications. Discontinue two weeks prior to surgery or if any adverse reaction occurs. Do not use if safety seal is missing.
Keep out of reach of children.
Chromax®, including the Chromax® logo, is a registered
trademark of Nutrition21, LLC. Chromax® is patent protected.
Crominex® 3+, Capros® and PrimaVie® are
registered trademarks of Natreon, Inc.
TamaFlex® is a
trademark of NXT USA, Inc., U.S. Patent # 11,147,850.
Science and Quality
Magnesium Glycinate Complex
Magnesium is an essential nutrient that is necessary for many metabolic activities, including promoting physical health in those struggling with low mood linked to magnesium deficiency.
Magnesium is readily available through food. Good dietary sources include dairy products, fish, meat, and seafood. It is also abundant in many fruits and vegetables, and whole grains and herbs. Yet, most Americans do not consume enough of this important mineral, and deficiencies are common.1
Our magnesium glycinate complex includes two absorbable forms of magnesium—glycinate and oxide—which are essential for healthy blood sugar*, blood pressure levels*, blood flow, and healthy arteries, plus magnesium is a key component of bones and helps maintain a healthy heart rhythm, nerve function, smooth muscle, and more. Plus, it’s a gentler formula compared to other forms.2
Magnesium does all this and unfortunately, age, stress, poor diet, and environmental pollutants can deplete it.
TamaFlex®
TamaFlex is a synergistic herbal blend of extracts from Tamarindus indica fruit seeds (e.g., tamarind) and Curcuma longa rhizome (e.g., turmeric), and is standardized to at least 65% polyphenolic proanthocyanins and 3% total curcuminoids. The tamarind is combined with turmeric to create a powerful plant-based, patented combination that has powerful joint-supporting benefits.
In three distinct studies of subjects with either mild-to-moderate knee discomfort or knee discomfort after physical exertion, participants were given either 250 mg of TamaFlex or placebo. Those taking TamaFlex showed a significant change vs. placebo after 5 days and at additional intervals ranging from 14 to 90 days. The TamaFlex group showed a significant change in several markers of joint health and comfort, resulting in fast relief that improved over time. Daily5 delivers the full 250 mg research dose of TamaFlex.3,4
The studies for TamaFlex used the WOMAC index, the gold standard of testing protocol for joint health research. The WOMAC index is divided into three sub-scores for 1) discomfort, 2) stiffness and 3) physical function. The Lequesne Functional Index (LFI) was also used—an index of severity of discomfort of the knee, consisting of three components: 1) discomfort, 2) maximum distance walked, and 3) activities of daily living.
Coenzyme Q10 (as ubiquinone)®
CoQ10 is critical for energy at the cellular level, supports cholesterol, triglycerides, and metabolic health, improves blood pressure*, and promotes better skin in women. And it replenishes depletions caused by statin medications and aging.
Resveratrol (from Japanese Knotweed Root Extract)®
The resveratrol in Daily5 provides antioxidant support and benefits your cardiovascular health, circulatory system, and boosts blood flow in as little as 1 hour! Healthy blood flow is perhaps the single most important factor for the health of every organ in your body.
In a study, 20 overweight adults aged 30–70 years old supplemented with 30 mg of resveratrol and their flow-mediated dilation (FMD), a biomarker of blood flow, endothelial function, and cardiovascular health, was observed 1 hour after consumption. Results showed that each dose of resveratrol had a significant increase in FMD. Resveratrol also had a significant dose effect on the plasma resveratrol concentration.5
Chromax® chromium picolinate and Crominex® 3+®
Chromium is an essential trace element that is required for normal fat and carbohydrate metabolism and overall metabolic health. Chromium may help promote a healthy body composition in resistance-trained men.
Daily5 delivers two high potency forms of chromium—Chromax® chromium picolinate and Crominex® 3+. Chromax chromium picolinate is shown to be up to 15X more absorbable than other forms of chromium.
*Healthy support for levels already within the normal range.
1 Sinatra S, et al. Heart Sense for Women. Washington, DC: LifeLine Press; 2000.
2 Guerrero-Romero, 2015.
3 Kare, S.K., et al. (2022). Evidence-Based Complementary and Alternative Medicine, 2226139.
4 Rao, P.S., et al. (2019). International Journal of Medical Sciences, 16(6), 845–853.
5 Wong, 2011.
Product Quality
- Each ingredient's potency is verified. View the Certificate of Analysis.
- Manufactured to exacting standards using highest quality raw materials
- Produced under our own SOPs that meet FDA GMPs
- Every batch tested to verify purity and potency specifications are met
- Quality assured with our Triple-Testing Philosophyâ„¢
- Backed by our 100% satisfaction guarantee
What makes Daily5 different from other healthy aging supplements?
Read More
The formula was developed by Dr. Drew Sinatra to help address some of the most common wellness concerns that arise with age. By supporting multiple systems throughout the body, Daily5 offers a convenient, science-backed approach to healthy aging.
What are the 5 ingredients in Daily5 and what do they do?
Read More
• CoQ10 helps support cellular energy production and cardiovascular health.
• Magnesium provides a highly absorbable form of magnesium that supports muscle, nerve, and metabolic function.
• Chromium is involved in healthy carbohydrate and lipid metabolism.
• TamaFlex®, a proprietary blend of turmeric and tamarind extracts, has been clinically validated for supporting joint comfort, flexibility, and mobility.
Together, these ingredients work across multiple body systems to help support healthy aging, energy levels, circulation, mobility, and metabolic wellness.
How does Daily5 support energy production?
Read More
Research shows that CoQ10 levels may decline with age, which is one reason many people seek supplementation as part of a healthy aging routine. Daily5 also provides magnesium glycinate, a form of magnesium known to be involved in many pathways throughout the body, including those related to mood.
By providing both CoQ10 and magnesium, Daily5 helps support the body's natural energy production pathways, positive mood, and overall vitality as part of a healthy lifestyle.
What is CoQ10 and why does it decline with age?
Read More
Studies have shown that CoQ10 production may decrease as people get older. Certain lifestyle factors and medications may also affect CoQ10 levels, including statin drugs. Because of its importance for energy production and cardiovascular wellness, many healthcare practitioners recommend CoQ10 supplementation as part of a healthy aging plan.
Daily5 includes CoQ10 to help support healthy energy production, cardiovascular function, and overall vitality.
Can Daily5 help support heart health?
Read More
Daily5 also contains a magnesium glycinate complex, a highly absorbable form of magnesium that supports normal muscle function, including the muscles involved in cardiovascular activity. Magnesium is involved in numerous physiological processes that contribute to overall cardiovascular health.
Together, these ingredients provide nutritional support for heart health while also helping support healthy aging. Daily5 is not intended to treat or prevent cardiovascular disease, but it can be a valuable addition to a wellness routine focused on supporting cardiovascular function.
What is endothelial function and why is it important?
Read More
As we age, endothelial function may naturally decline due to oxidative stress and other lifestyle factors. Research has shown that ingredients such as resveratrol and CoQ10 can help support healthy endothelial function and vascular health. Daily5 includes both of these research-backed key ingredients to help support circulation and healthy blood flow as part of a comprehensive healthy aging routine.
How does Daily5 support healthy circulation?
Read More
The formula also includes CoQ10 and a magnesium glycinate complex, which support cardiovascular wellness and endothelial health. Together, these ingredients help maintain healthy blood vessel function and support efficient circulation throughout the body. By supporting healthy blood flow, Daily5 helps promote overall vitality and healthy aging.
How quickly can Daily5 start working?
Read More
One of Daily5's most unique ingredients is TamaFlex®, a proprietary blend of turmeric and tamarind extracts. Clinical studies found participants experienced measurable improvements in joint comfort, flexibility, and physical function in as little as five days. Other ingredients, such as CoQ10, magnesium, chromium, and resveratrol, provide support through consistent daily use as they help maintain healthy cellular function, metabolic health, circulation, and cardiovascular wellness.
For best results, Daily5 should be taken consistently as part of a healthy lifestyle.
Can Daily5 help support joint comfort and mobility?
Read More
Research found that TamaFlex® helped support joint comfort, flexibility, knee range of motion, and physical function compared with placebo. Participants experienced improvements in mobility-related measures and reported greater ease of movement during daily activities. Some benefits were observed within just five days, making TamaFlex® one of the fastest-acting key ingredients in the formula.
By including TamaFlex® alongside nutrients that support energy production, circulation, and metabolic health, Daily5 provides a comprehensive approach to supporting active aging and overall wellness.
What is TamaFlex® and why is it included in Daily5?
Read More
Clinical studies have shown that TamaFlex® can help support joint comfort, flexibility, range of motion, and physical performance. Researchers observed significant improvements compared with placebo, including benefits that appeared in as little as five days. These findings make TamaFlex® one of the most distinctive ingredients in the Daily5 formula.
Healthy Directions selected TamaFlex® because maintaining comfortable movement and physical activity is essential for healthy aging. By supporting joint function and mobility, TamaFlex® helps complement the formula's support for energy, circulation, cardiovascular health, and metabolic wellness.
How does Daily5 support healthy blood sugar and metabolic health?
Read More
Research cited in the Daily5 dossier found that chromium and magnesium may help support healthy metabolic markers. By providing targeted nutritional support for blood sugar and cellular energy production, Daily5 helps promote overall metabolic wellness and healthy aging.
What role does chromium play in Daily5?
Read More
As people age, maintaining healthy metabolic function becomes increasingly important. Daily5 includes chromium to help support healthy glucose levels and overall metabolic wellness. The formula provides chromium in two complementary forms that have been validated for their metabolic benefits and effectiveness.
When combined with magnesium and other ingredients in Daily5, chromium helps support the body's own metabolic processes and contributes to the formula's comprehensive healthy aging benefits.
Why does Daily5 contain two forms of chromium?
Read More
Chromax® is one of the most researched forms of supplemental chromium and has been validated for its role in supporting healthy glucose balance and insulin activity. Crominex® 3+ combines chromium with additional antioxidant compounds to provide broader metabolic support. By incorporating both forms, Daily5 delivers a thoughtful approach to supporting healthy metabolic function and blood sugar.
This dual-chromium strategy reflects the overall Daily5 philosophy of combining research-backed key ingredients to support multiple aspects of healthy aging, energy production, and metabolic wellness.
What does magnesium glycinate do for the body?
Read More
Daily5 provides magnesium in the glycinate form, which is known for its excellent gastrointestinal tolerability. Research referenced in the Daily5 dossier suggests that magnesium may help support healthy blood pressure, glucose levels, cardiovascular function, and overall metabolic health.
Because magnesium participates in so many critical biological processes, maintaining healthy levels can have broad wellness benefits. Daily5 includes 420 mg of magnesium to help address a common nutritional gap and support healthy aging.
Why is magnesium deficiency so common after age 50?
Read More
Several factors can contribute to lower magnesium status over time, including reduced dietary intake, age-related changes in absorption, and lifestyle factors. Because magnesium is required for hundreds of biological processes, even modest deficiencies can affect overall wellness.
Daily5 was formulated with 420 mg of magnesium glycinate to help support healthy magnesium status and provide nutritional support for many of the body's most important physiological functions.
Is Daily5 beneficial for people taking statins?
Read More
For this reason, many healthcare practitioners recommend considering CoQ10 supplementation as part of a wellness plan for individuals taking statins. Daily5 provides 200 mg of CoQ10 to help support healthy cellular energy production and cardiovascular wellness. While Daily5 is not intended to replace medical treatment or manage medication side effects, it may help support healthy CoQ10 levels as part of a comprehensive healthy aging routine. Individuals taking prescription medications should consult their healthcare provider before beginning any supplement program.
Who should take Daily5?
Read More
The formula combines clinically researched key ingredients that address areas where nutritional needs may increase over time, including CoQ10 and magnesium. It may be particularly appealing for adults who want a convenient way to support healthy aging without taking multiple separate supplements. Whether you're focused on staying active, maintaining cardiovascular wellness, supporting healthy metabolic function, or promoting overall vitality, Daily5 offers a comprehensive approach to daily nutritional support.
Can Daily5 replace a multivitamin?
Read More
Many multivitamins either do not include these ingredients or provide them in relatively small amounts. For that reason, Daily5 can be an excellent complement to a quality multivitamin. Whether it can replace a multivitamin depends on your individual nutritional needs and healthcare provider's recommendations. Daily5 is best viewed as a targeted healthy aging formula designed to support wellness beyond basic nutrition.
Why was Daily5 developed by Dr. Drew Sinatra?
Read More
Daily5 was created to simplify that process by bringing together five clinically researched ingredients that support some of the most important pillars of healthy aging. The formula was designed to provide targeted support for cellular energy production, cardiovascular wellness, healthy circulation, glucose levels, and joint comfort.
By combining research-backed ingredients into a single daily formula, Dr. Sinatra sought to create a convenient way for adults to support lasting vitality, mobility, and overall wellness as part of a healthy lifestyle.
How does Daily5 support healthy aging overall?
Read More
The formula contains CoQ10 to support cellular energy production, magnesium glycinate to support cardiovascular and metabolic function, chromium to help maintain healthy glucose levels, and TamaFlex® to promote joint comfort and mobility. It also includes resveratrol, which supports circulation and vascular wellness.
Together, these ingredients help support many of the biological processes associated with aging well. By providing targeted nutritional support across multiple body systems, Daily5 offers a science-backed approach to helping adults maintain wellness, activity, and quality of life as they age.
Product reviews and ratings are provided for informational purposes only and reflect solely the views and opinions expressed by the individual contributors and not those of Healthy Directions LLC. Healthy Directions LLC neither verifies nor endorses any claims made in these reviews and ratings.

