Item #CHS01
Dr. Stephen Sinatra
Advanced Cholesterol Solutions®
Powerful citrus fruit extract promotes healthy cholesterol ratios and supports heart health!
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Additional Product Details
Powerful citrus extract delivers cholesterol-balancing benefits
Cardiologist formulated
Healthy cholesterol ratios
Quality assured
Healthy heart & arteries
When it comes to cholesterol, balance is key
Cholesterol is ESSENTIAL to so many functions in your body—including heart health, blood sugar, and the integrity of key cells in your body. But focusing on just your total cholesterol is not enough. For true heart and artery support, you need to tackle the blood lipids that make up your total cholesterol—HDL, LDL, and triglycerides. And this formula helps to balance all of these numbers for optimal health.
Clinically studied Bergamonte for healthy triglycerides, HDL, LDL and more!
In a double-blind, placebo-controlled study, Bergamonte, an extract of the citrus bergamot orange, supported participants' healthy triglyceride levels. It also provided support for HDL (“good cholesterol”) and LDL (“bad cholesterol”) along with blood glucose levels. This is all vital to maintaining healthy cholesterol levels and the health of your heart.
Full-spectrum coverage without depleting nutrients
Each dose of Advanced Cholesterol Solutions supports key cholesterol and lipid blood levels while also supporting vascular health, blood flow, and blood sugar levels. And, unlike other solutions, this formula does all this without depleting important nutrients your heart and body need to function and feel well.
Italian fruit extract tackles many cholesterol markers at once!
Advanced Cholesterol Solutions’ star ingredient is Bergamonte, a remarkable citrus extract from the southern coast of Italy. It works in the liver, to help keep your cholesterol levels in a healthy range. It supports everything from balanced, healthy total cholesterol levels to lower LDL (“bad”), higher HDL (“good”), healthy triglycerides, and normal blood sugar levels.
2 “oxidation”-fighting antioxidants
Antioxidant support to help fight oxidation is vital to the health of your heart and entire body. Every dose of this formula provides a potent vitamin E complex (with both tocopherols and tocotrienols) for antioxidant support plus 50 mg of vitamin C to provide support against free radicals.
Full-spectrum heart and artery support
Not only do you get support for healthy total cholesterol, LDL, HDL, and triglyceride levels, you’re also getting support for blood flow, endothelial function, vascular health, and blood sugar levels. Blood sugar support is especially important since it often gets overlooked when conventional doctors are assessing your overall cholesterol and heart health.
Italian fruit extract tackles many cholesterol markers at once!
2 “oxidation”-fighting antioxidants
Full-spectrum heart and artery support
Formulated by Integrative Cardiologist Stephen Sinatra, M.D.
A true pioneer, Dr. Sinatra spent more than 40 years in clinical practice, including serving as an attending physician and chief of cardiology at Manchester Memorial Hospital, then going on to formulate his advanced line of heart health supplements. His integrative approach to heart health has changed the lives of hundreds of thousands.
Ingredients and Dosage
Doctor's Suggested Use: Take one (1) capsule daily, preferably before a meal. For additional support, take one (1) capsule twice daily.
Serving Size: 1 Capsule
Servings Per Container: 30
| Ingredient | Amount Per Serving | % DV |
|---|---|---|
| Vitamin C (as ascorbic acid, as ascorbic acid (from Bergamonte®)) | 50 mg | 56% |
|
Bergamot Orange Extract (whole fruit) (38% polyphenols comprised of neoeriocitrin, naringin, and neohesperidin, melitidine, brutelidine)(Bergamonte®) |
500 mg | * |
| Tocotrienol and Tocopherol Complex (from African oil palm fruit) | 10 mg | * |
| * Daily Value (DV) not established | ||
Other ingredients: Gelatin, microcrystalline cellulose and vegetable magnesium stearate.
Precautions: Consult a health care practitioner before use if you are pregnant or nursing, have a serious medical condition, or use any medications. Discontinue use two weeks prior to surgery or if any serious adverse reaction occurs. Do not use if safety seal is missing.
Keep out of reach of children.
Gluten Free
Science and Quality
The importance of cholesterol
Cholesterol is a soft, wax-like substance that is found in each of your cells, as well as in your bloodstream. Approximately 75% of it is produced in your liver and about 25% comes from diet. Your body needs cholesterol to:
- synthesize vitamin D
- produce hormones and digestive acids
- keep your cell membranes functioning properly
It's important to maintain healthy cholesterol levels for a strong cardiovascular system, as well as overall good health.
Double-blind, placebo-controlled study results
- Bergamonte polyphenolic fraction (BPF) was compared to a placebo in a study of 237 men and women. In the double-blind study, researchers divided subjects into 3 different groups. Each group was divided into 3 subgroups and received either 500 mg/day BPF (69 subjects), 1,000 mg/day BPF (70 subjects), or placebo (66 subjects) for 30 days. At the end of the trial, researchers found BPF:
- Helped promote healthy total cholesterol, LDL cholesterol, and triglycerides
- Supported healthy LDL cholesterol levels
- Supported healthy blood glucose levels (all results statistically significant compared to placebo)
- The same study confirms that double the dose of Bergamonte (1,000 mg) was even more effective at supporting key blood lipid markers, as well as supporting LDL cholesterol molecules against oxidation, proving this remarkable citrus extract an effective option for improving critical measurements of heart health.
Product Quality
- Each ingredient's potency is verified. View the Certificate of Analysis.
- Manufactured to exacting standards using highest quality raw materials
- Produced in accordance with our strict Standard Operating Procedures (SOPs) that meet those set by the FDA’s Good Manufacturing Practices
- Every batch tested to verify purity and potency specifications are met
- Quality assured with our Triple-Testing Philosophy™
- Backed by our 100% satisfaction guarantee
What is Dr. Sinatra Advanced Cholesterol Solutions?
Read More
Unlike many cholesterol supplements that focus on a single ingredient, Advanced Cholesterol Solutions was designed to support multiple aspects of cardiovascular wellness. Research on its key ingredients has shown benefits related to healthy LDL cholesterol levels already within the normal range, endothelial function, nitric oxide production, antioxidant activity, and vascular health. The convenient one-capsule daily formula provides targeted nutritional support for adults looking to proactively maintain heart health as part of a healthy lifestyle.
How does bergamot help support cholesterol levels?
Read More
Clinical research on Bergavit®40 has demonstrated support for healthy LDL cholesterol and total cholesterol levels already within the normal range. In human studies, researchers observed significant improvements in key cholesterol markers compared with placebo. Additional research has shown benefits related to antioxidant protection, including support for healthy PON1 activity and reduced oxidation of LDL particles. This combination of cholesterol and antioxidant support makes bergamot a unique ingredient for comprehensive cardiovascular wellness.
What makes Advanced Cholesterol Solutions different from other cholesterol supplements?
Read More
In addition to supporting healthy LDL and total cholesterol levels already within the normal range, the formula is designed to support endothelial function, nitric oxide production, antioxidant activity, vascular health, healthy inflammatory response, and healthy systolic blood pressure already within the normal range. The formula also contains clinically validated doses used in published human research.
Another key differentiator is its doctor-formulated heritage. Developed with Dr. Stephen Sinatra's heart health philosophy, the formula focuses on supporting multiple cardiovascular pathways rather than concentrating on cholesterol alone.
Can Advanced Cholesterol Solutions help support healthy LDL cholesterol levels?
Read More
In human research, Bergavit®40 demonstrated significant improvements in LDL cholesterol measurements compared with placebo. Additional studies on bergamot ingredients have also shown support for total cholesterol and other lipid-related markers. The formula also includes Crominex®3+, which has been validated for supporting healthy lipid profiles and cardiovascular wellness.
Advanced Cholesterol Solutions is intended to help maintain cholesterol levels already within the normal range when combined with healthy diet and lifestyle habits.
How long does it take to see results from Advanced Cholesterol Solutions?
Read More
Studies involving Crominex®3+ reported changes in endothelial function, nitric oxide levels, lipid markers, and antioxidant markers after approximately 12 weeks. Research on Bergavit®40 demonstrated support for LDL cholesterol and total cholesterol at approximately 3 months, with additional benefits related to antioxidant activity and healthy systolic blood pressure observed at around 4 months. Longer-term studies also reported meaningful cholesterol-related benefits after 6 months of use.
For best results, take the formula daily as directed and combine it with heart-healthy lifestyle practices.
Is Advanced Cholesterol Solutions a statin?
Read More
Instead, the formula relies on two clinically validated ingredients: Bergavit®40 bergamot extract and Crominex®3+ chromium. Research on these ingredients has demonstrated support for healthy LDL cholesterol and total cholesterol levels already within the normal range, along with benefits related to vascular health, antioxidant activity, nitric oxide production, and endothelial function.
Many consumers choose nutritional supplements as part of a broader heart-health strategy that includes a healthy diet, exercise, weight management, and regular medical care. Always consult your healthcare provider before making changes to your health regimen or prescription medications.
What are the ingredients in Advanced Cholesterol Solutions?
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Bergavit®40 (385 mg) is a bergamot orange fruit extract standardized to provide 39% flavonoids, including neoeriocitrin, naringin, and neohesperidin. Bergamot has been clinically validated for supporting healthy LDL cholesterol and total cholesterol levels already within the normal range.
Crominex®3+ Chromium (200 mcg) combines chromium with Capros® amla extract and PrimaVie® purified shilajit. Research has evaluated its effects on endothelial function, nitric oxide production, antioxidant status, healthy inflammatory response, and healthy glycemic control.
Together, these ingredients provide a multi-targeted approach to supporting cardiovascular wellness and healthy aging.
What is Bergavit®40 bergamot extract?
Read More
Human clinical studies have investigated Bergavit®40 for its ability to support healthy LDL cholesterol and total cholesterol levels already within the normal range. Additional research has demonstrated support for antioxidant defenses through improvements in markers such as PON1 activity and oxidized LDL.
Because of its high flavonoid content and clinical research backing, Bergavit®40 has become one of the most validated bergamot ingredients available for cardiovascular support.
What is Crominex®3+ chromium and why is it included?
Read More
Clinical research involving Crominex®3+ has evaluated its effects on several important cardiovascular and metabolic markers. Investigators observed benefits related to endothelial function, nitric oxide levels, cholesterol markers, antioxidant status, inflammatory response markers, and glycemic control.
In Advanced Cholesterol Solutions, Crominex®3+ complements bergamot by supporting vascular function and cardiovascular wellness beyond cholesterol alone. This combination helps create a broader heart-health formula that addresses multiple pathways involved in healthy aging and cardiovascular performance.
How does Advanced Cholesterol Solutions support cardiovascular health?
Read More
Advanced Cholesterol Solutions was formulated to support several of these interconnected pathways. Bergavit®40 helps support healthy LDL cholesterol and total cholesterol levels already within the normal range while also supporting antioxidant defenses. Crominex®3+ has been validated for its role in supporting endothelial function, nitric oxide production, healthy inflammatory response, and vascular health.
This multi-faceted approach reflects Dr. Sinatra's philosophy that comprehensive cardiovascular support should address multiple aspects of heart and vascular wellness rather than focusing on a single biomarker.
How does Advanced Cholesterol Solutions support healthy endothelial function?
Read More
Research on Crominex®3+ evaluated markers associated with endothelial function and vascular wellness. In a clinical study, participants receiving Crominex®3+ demonstrated improvements in a measure known as the reflective index, which researchers use to assess endothelial function.
Because healthy endothelial function supports healthy blood vessel performance and circulation, Advanced Cholesterol Solutions was formulated to provide benefits that extend beyond traditional cholesterol support alone.
Does Advanced Cholesterol Solutions support nitric oxide production?
Read More
In clinical research, Crominex®3+ was associated with improvements in nitric oxide levels, a key marker of endothelial and vascular function. Researchers often evaluate nitric oxide because it is closely linked to healthy circulation and cardiovascular performance.
By including Crominex®3+ alongside Bergavit®40 bergamot extract, Advanced Cholesterol Solutions supports multiple cardiovascular pathways, including cholesterol levels, vascular function, antioxidant defenses, and nitric oxide production.
What is oxidized LDL and why is it important?
Read More
Research on Bergavit®40 found support for antioxidant protection related to oxidized LDL levels. This is significant because maintaining healthy LDL particles may be just as important as supporting healthy LDL cholesterol levels themselves.
The bergamot extract in Advanced Cholesterol Solutions contains naturally occurring citrus flavonoids that provide antioxidant activity. This gives the formula a unique advantage compared with supplements that focus exclusively on cholesterol numbers without addressing antioxidant protection and vascular wellness.
How does Advanced Cholesterol Solutions provide antioxidant support?
Read More
The ingredients in Advanced Cholesterol Solutions have been validated for multiple antioxidant-related benefits. Research on Bergavit®40 demonstrated support for healthy PON1 activity, an enzyme associated with HDL function and antioxidant protection. Studies also evaluated support for protection against cholesterol oxidation.
Research involving Crominex®3+ demonstrated support for healthy glutathione levels, one of the body's most important natural antioxidants, along with improvements in biomarkers associated with oxidative stress.
Together, these ingredients provide broad antioxidant support for cardiovascular wellness.
Does Advanced Cholesterol Solutions support healthy blood pressure?
Read More
Systolic blood pressure refers to the pressure exerted against artery walls when the heart beats. Maintaining healthy levels is important for extended cardiovascular health.
This additional benefit highlights the broader cardiovascular support provided by bergamot extract. Rather than focusing exclusively on cholesterol, Advanced Cholesterol Solutions supports multiple aspects of heart and vascular wellness, including cholesterollevels, antioxidant defenses, endothelial function, nitric oxide production, and healthy blood pressure already within the normal range.
Can Advanced Cholesterol Solutions support healthy inflammation levels?
Read More
Clinical research involving Crominex®3+ examined changes in hsCRP alongside other cardiovascular and metabolic markers. Results demonstrated support for maintaining healthy inflammatory-response markers.
This benefit complements the formula's support for cholesterol levels, endothelial function, nitric oxide production, and antioxidant defenses. By addressing multiple aspects of cardiovascular wellness, Advanced Cholesterol Solutions provides a more comprehensive approach than supplements that focus on cholesterol alone.
Who should take Advanced Cholesterol Solutions?
Read More
The formula combines clinically validated Bergavit®40 bergamot extract and Crominex®3+ chromium, ingredients that have been researched for multiple cardiovascular benefits. Unlike formulas that focus on a single marker, Advanced Cholesterol Solutions supports several interconnected aspects of heart health.
As with any dietary supplement, individuals who are pregnant, nursing, have a medical condition, or take medications should consult a healthcare professional before use.
Can I take Advanced Cholesterol Solutions with other heart health supplements?
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If you are already taking supplements for heart health, circulation, blood pressure, blood sugar support, or cholesterol management, discuss your regimen with your healthcare professional before adding a new supplement. This is particularly important if you are taking prescription medications or are being monitored for cardiovascular conditions.
Your healthcare provider can help determine whether Advanced Cholesterol Solutions is an appropriate addition to your overall wellness plan and can evaluate potential interactions based on your individual needs.
How many capsules of Advanced Cholesterol Solutions should I take each day?
Read More
Each capsule delivers 385 mg of Bergavit®40 bergamot extract and 200 mcg of Crominex®3+ chromium, the key ingredients responsible for the formula's cardiovascular benefits.
Consistency is important when using any nutritional supplement. Clinical studies evaluating the formula's ingredients assessed outcomes over periods ranging from approximately 12 weeks to 6 months, making regular daily use an important part of achieving the intended benefits.
Is Advanced Cholesterol Solutions backed by clinical research?
Read More
Research on Bergavit®40 demonstrated support for healthy LDL cholesterol and total cholesterol levels already within the normal range, along with benefits related to antioxidant protection and healthy systolic blood pressure. Studies involving Crominex®3+ evaluated endothelial function, nitric oxide production, lipid markers, healthy inflammatory response, antioxidant status, and glycemic control.
Together, these studies provide scientific support for the formula's comprehensive cardiovascular health positioning.
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