Item #BER01

Dr. Julian Whitaker

Clinical Grade Berberine (1500mg)

Help maintain normal blood sugar and cholesterol levels with this clinical grade berberine supplement

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Additional Product Details

Original Berberine Helps Maintain Healthy Blood Sugar and Cholesterol Levels

Whitaker Nutrition Berberine is derived from a natural plant alkaloid found in goldenseal, barberry, goldthread, and Oregon grape. It works at the cellular level to support healthy blood sugar. This well-tolerated extract has been shown to be an effective alternative for promoting healthy blood sugar levels already in the normal range, even after eating a meal or a sugary treat. The plant alkaloid berberine has become one of the #1 recommended ingredients in traditional Chinese and Ayurvedic medicine but largely ignored elsewhere until very recently. It is our top ingredient to help maintain normal blood sugar and lipid levels.

What does the research say about Berberine?

A two-part study showed that 1,500 mg of Berberine daily supports normal fasting and postprandial blood glucose levels already in the normal range, along with 3-month average healthy blood sugar levels.1 A second randomized, double-blind placebo-controlled study (where individuals took three 500 mg doses of berberine daily) also confirmed that berberine helps maintain blood sugar levels already in the normal range.2

That’s because Clinical Grade Berberine works by targeting a key regulator of metabolism, the activated protein kinase (AMPK) enzyme. AMPK regulates glucose uptake by your cells and the synthesis of glucose transporters—which helps move glucose out of your blood and into your cells, where it belongs.

Berberine may also increase the number and activity of the insulin receptors on your cells, supporting insulin sensitivity. On top of that, AMPK facilitates the burning of fatty acids in your cells, which is why it’s a powerful tool for helping keep blood lipid levels in check.

Berberine supports healthy triglycerides, LDL cholesterol and total cholesterol—but not all berberine is created equal!

Up until now it’s been almost impossible to find a berberine supplement that provides the research level of 1,500 mg daily. That's why Dr. Whitaker's Clinical Grade Berberine, with high-quality BerberPure™ Berberine, is such an effective supplement for blood sugar support. Plus, BerberPure Berberine is sourced globally, and manufactured and triple-tested in the USA.

What Our Customers Say:

"I am delighted to be able to recommend Berberine. I rate this product five stars. I cannot speak more highly of it. I want everyone to try it for several months and see the amazing results."*

— Online Review

"[…] My overall numbers are normal and I feel great. I love this product and will never take anything else."*

— Online Review

"I have never had a blood sugar product nearly as good as Berberine […]."*

— Online Review

*Results not Typical.

1Yin J, et al. Metabolism 2008;57(5):712–17.
2Pérez-Rubio, K. G. et al. Metab. Syndr. Relat. Disord. 2013;11:366–9.

Ingredients and Dosage

Doctor's Suggested Use: Take 3 capsules daily—1 before each meal.

Serving Size: 1 Capsule
Servings Per Container: 90


Amount Per Serving

Berberine Hydrochloride (BerberPure)

500 mg

Other ingredients: Microcrystalline cellulose, gelatin, magnesium stearate, gum acacia, silica

Precautions: Consult a health care practitioner before use if you are on insulin or are hypoglycemic, are pregnant or nursing, have a serious medical condition, or use any other medications.

Keep out of reach of children.

  • Gluten Free

BerberPure™ is a trademark of Healthy Directions.

Science and Quality

Where does this amazing phytonutrient come from?

Berberine is a plant alkaloid, a naturally occurring chemical compound found in herbs such as goldenseal, Oregon grape, barberry, and goldthread. While you may be able to find berberine in a few supplements here and there, it’s rare and unlikely you’ll find the dose that helps maintain normal blood sugar levels—which means a lot of folks are missing out on the most powerful benefits.

That changes with Clinical Grade Berberine supplement formula, as it gives you the full research dose of 1,500 mg, shown to help support blood sugar, cholesterol, and triglyceride levels already in the normal range.

Berberine Supports Healthy Blood Sugar and More!

In one part of a two part study, individuals were given three 500 mg doses of berberine daily (the same dose in Berberine+ GlucoGold) for three months. Research showed that berberine supports a healthy blood glucose response to a meal. In the second part of this study, individuals were also given three 500 mg doses of berberine daily and the trial showed that berberine helps maintain blood sugar levels already in the normal range, supports a healthy blood lipid profile, and supports healthy total and LDL cholesterol levels.1

1Zhao W, et al. Biomed Pharmacother 2008;62(10):730–1.

Product Quality

In addition, Berberine is manufactured under stringent quality controls:

  • Manufactured to exacting standards using highest quality raw materials
  • Produced in accordance with our strict Standard Operating Procedures (SOPs) that meet those set by the FDA’s Good Manufacturing Practices
  • Every batch tested to verify purity and potency specifications are met
  • Quality assured with our Triple-Testing Philosophy™
  • Backed by our 100% satisfaction guarantee

Product reviews and ratings are provided for informational purposes only and reflect solely the views and opinions expressed by the individual contributors and not those of Healthy Directions LLC. Healthy Directions LLC neither verifies nor endorses any claims made in these reviews and ratings.